BIOL 477 - Genomics and Bioinformatics

4 Credit(s)

This course is designed to provide students with an in-depth understanding of comparative and functional genomics and practice using genomics and bioinformatics tools. Topics discussed include structure and anatomy of DNA elements, sequencing and other methods used in decoding DNA, genes, and entire genomes, gene expression profiling, gene annotation, homology, clusters of ortholog genes, protein structure function, high throughput functional assays, and experimental perturbation of genomes for medical purposes. Examples presented in the course illustrate the role of functional genomics in drug design, gene discovery, and in designing individual therapies for a variety of diseases and disorders. Laboratory exercises will give students experience in handling and interpreting biological data using various computational methods.

Prerequisite(s):
CHEM 401 Minimum Grade: C- OR T

AND

BIOL 476 Minimum Grade: C- OR T